We describe factors determining retention and survival among HIV-infected children and adolescents engaged in two health care\r\ndelivery models in Kampala, Uganda: one is a community home-based care (CHBC) and the other is a facility-based familycentred\r\napproach (FBFCA). This retrospective cohort study reviewed records from children aged from 0 to 18 years engaged in\r\nthe two models from 2003 to 2010 focussing on retention/loss to follow-up, mortality, use of antiretroviral therapy (ART), and\r\nclinical characteristics. KaplanMeier survival curves with log rank tests were used to describe and compare retention and survival.\r\nOverall, 1,623 children were included, 90.0% (1460/1623) from the CHBC. Children completed an average of 4.2 years of followup\r\n(maximum 7.7 years). Median age was 53 (IQR: 11ââ?¬â??109) months at enrolment. In the CHBC, retention differed significantly\r\nbetween patients on ART and those not (log-rank test, adjusted, P< 0.001). Comparing ART patients in both models, there was\r\nno significant difference in long-term survival (log-rank test, P = 0.308, adjusted, P = 0.489), while retention was higher in the\r\nCHBC: 94.8% versus 84.7% in the FBFCA (log-rank test, P < 0.001, adjusted P= 0.006). Irrespective of model of care, children\r\nreceiving ART had better retention in care and survival.
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